Neither Hubble nor Einstein would be much of a part of that big story. Though no one would have guessed it at the time, both men had done about as much as they were ever going to do.

In 1936 Hubble produced a popular book called The Realm of the Nebulae, which explained in flattering style his own considerable achievements. Here at last he showed that he had acquainted himself with Einstein’s theory-up to a point anyway: he gave it four pages out of about two hundred.

Hubble died of a heart attack in 1953. One last small oddity awaited him. For reasons cloaked in mystery, his wife declined to have a funeral and never revealed what she did with his body. Half a century later the whereabouts of the century’s greatest astronomer remain unknown. For a memorial you must look to the sky and the Hubble Space Telescope, launched in 1990 and named in his honor.

WHILE EINSTEIN AND Hubble were productively unraveling the large-scale structure of the cosmos, others were struggling to understand something closer to hand but in its way just as remote: the tiny and ever- mysterious atom.

The great Caltech physicist Richard Feynman once observed that if you had to reduce scientific history to one important statement it would be “All things are made of atoms.” They are everywhere and they constitute every thing. Look around you. It is all atoms. Not just the solid things like walls and tables and sofas, but the air in between. And they are there in numbers that you really cannot conceive.

The basic working arrangement of atoms is the molecule (from the Latin for “little mass”). A molecule is simply two or more atoms working together in a more or less stable arrangement: add two atoms of hydrogen to one of oxygen and you have a molecule of water. Chemists tend to think in terms of molecules rather than elements in much the way that writers tend to think in terms of words and not letters, so it is molecules they count, and these are numerous to say the least. At sea level, at a temperature of 32 degrees Fahrenheit, one cubic centimeter of air (that is, a space about the size of a sugar cube) will contain 45 billion billion molecules. And they are in every single cubic centimeter you see around you. Think how many cubic centimeters there are in the world outside your window-how many sugar cubes it would take to fill that view. Then think how many it would take to build a universe. Atoms, in short, are very abundant.

They are also fantastically durable. Because they are so long lived, atoms really get around. Every atom you possess has almost certainly passed through several stars and been part of millions of organisms on its way to becoming you. We are each so atomically numerous and so vigorously recycled at death that a significant number of our atoms-up to a billion for each of us, it has been suggested-probably once belonged to Shakespeare. A billion more each came from Buddha and Genghis Khan and Beethoven, and any other historical figure you care to name. (The personages have to be historical, apparently, as it takes the atoms some decades to become thoroughly redistributed; however much you may wish it, you are not yet one with Elvis Presley.)

So we are all reincarnations-though short-lived ones. When we die our atoms will disassemble and move off to find new uses elsewhere-as part of a leaf or other human being or drop of dew. Atoms, however, go on practically forever. Nobody actually knows how long an atom can survive, but according to Martin Rees it is probably about 10³⁵ years-a number so big that even I am happy to express it in notation.

Above all, atoms are tiny-very tiny indeed. Half a million of them lined up shoulder to shoulder could hide behind a human hair. On such a scale an individual atom is essentially impossible to imagine, but we can of course try.

Start with a millimeter, which is a line this long: -. Now imagine that line divided into a thousand equal widths. Each of those widths is a micron. This is the scale of microorganisms. A typical paramecium, for instance, is about two microns wide, 0.002 millimeters, which is really very small. If you wanted to see with your naked eye a paramecium swimming in a drop of water, you would have to enlarge the drop until it was some forty feet across. However, if you wanted to see the atoms in the same drop, you would have to make the drop fifteen miles across.

Atoms, in other words, exist on a scale of minuteness of another order altogether. To get down to the scale of atoms, you would need to take each one of those micron slices and shave it into ten thousand finer widths. That’s the scale of an atom: one ten-millionth of a millimeter. It is a degree of slenderness way beyond the capacity of our imaginations, but you can get some idea of the proportions if you bear in mind that one atom is to the width of a millimeter line as the thickness of a sheet of paper is to the height of the Empire State Building.

It is of course the abundance and extreme durability of atoms that makes them so useful, and the tininess that makes them so hard to detect and understand. The realization that atoms are these three things-small, numerous, practically indestructible-and that all things are made from them first occurred not to Antoine-Laurent Lavoisier, as you might expect, or even to Henry Cavendish or Humphry Davy, but rather to a spare and lightly educated English Quaker named John Dalton, whom we first encountered in the chapter on chemistry.

Dalton was born in 1766 on the edge of the Lake District near Cockermouth to a family of poor but devout Quaker weavers. (Four years later the poet William Wordsworth would also join the world at Cockermouth.) He was an exceptionally bright student-so very bright indeed that at the improbably youthful age of twelve he was put in charge of the local Quaker school. This perhaps says as much about the school as about Dalton’s precocity, but perhaps not: we know from his diaries that at about this time he was reading Newton’s Principia in the original Latin and other works of a similarly challenging nature. At fifteen, still schoolmastering, he took a job in the nearby town of Kendal, and a decade after that he moved to Manchester, scarcely stirring from there for the remaining fifty years of his life. In Manchester he became something of an intellectual whirlwind, producing books and papers on subjects ranging from meteorology to grammar. Color blindness, a condition from which he suffered, was for a long time called Daltonism because of his studies. But it was a plump book called A New System of Chemical Philosophy, published in 1808, that established his reputation.

There, in a short chapter of just five pages (out of the book’s more than nine hundred), people of learning first encountered atoms in something approaching their modern conception. Dalton’s simple insight was that at the root of all matter are exceedingly tiny, irreducible particles. “We might as well attempt to introduce a new planet into the solar system or annihilate one already in existence, as to create or destroy a particle of hydrogen,” he wrote.

Neither the idea of atoms nor the term itself was exactly new. Both had been developed by the ancient Greeks. Dalton’s contribution was to consider the relative sizes and characters of these atoms and how they fit together. He knew, for instance, that hydrogen was the lightest element, so he gave it an atomic weight of one. He believed also that water consisted of seven parts of oxygen to one of hydrogen, and so he gave oxygen an atomic weight of seven. By such means was he able to arrive at the relative weights of the known elements. He wasn’t always terribly accurate-oxygen’s atomic weight is actually sixteen, not seven-but the principle was sound and formed the basis for all of modern chemistry and much of the rest of modern science.